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GSK

Image from left to right: (Top row) Anthony Lynch, Azmina Mather, Ciaran Fisher, Claire Teague, Crysthiane Ishiy, (Middle row) Daniel Sevin, Deidre Dalmas, Eric Rossman, Jan Roger, Jim Harvey, (Bottom row) Johanna Vappiani, Khuram Chaudhary, Kylie Beattie, Philippa Allen, Valeriu Damian.

How has GSK been involved in the TransQST project? We have actively contributed to each of the organ toxicity work packages (WP5-liver, WP6-kidney, WP7-heart and WP8-gastrointestinal system). Our contribution has included providing legacy datasets, data analysis, modelling, and the generation of novel data (using established and novel technologies) where the need has been identified. All […]

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ORION (ORION Corporation)

Image from left to right: Mikko Koskinen, Melina Malinen and Daniel Nicorici.

What is ORION’s main focus? Orion Corporation Orion Pharma is a globally operating Finnish pharmaceutical company. The core therapy areas of Orion’s pharmaceutical R&D are currently pain and oncology. When entering the first clinical trials with new molecular entities it is extremely important that we have applied the best state-of-the-art technologies for assessing the safety […]

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UKHD (Universitätsklinikum Heidelberg)

Bottom image from left to right: Denis Shapiro, Sebastian Lobentanzer, Katharina Zirngibl, Bartosz Bazmanszki, Denes Turei, Rosa Hernansaiz Ballesteros, Martín Garrido Rodríguez-Córdoba, Jovan Tanevski, Ahmet Sureyya Rifaioglu, Attila Gabor, Julio Saez-Rodriguez, Sophia Müller-Dott, Pau Badia i Mompel, Daniel Dimitrov.

What is the main focus of your group? At the Institute for Computational Biomedicine, we develop and apply computational methods to analyse complex biomedical data. Our goal is to acquire a functional understanding of molecular mechanisms in health and disease. We apply these insights to improve diagnosis and to develop novel therapeutics that we apply […]

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AbbVie

Top: Meredith E. Crosby, Sean C. Turner, Diana Clausznitzer.
Bottom: Panuwat Trairatphisan, Loic Laplanche, Stacey L. Fossey, Jennifer E. Mollon.

Contributors: Panuwat Trairatphisan Diana Clausznitzer What are your main research interests? In the Quantitative Translational Systems Pharmacology and Toxicology group, we aim to apply quantitative modeling and simulation methods to support the development of new medications and treatment modalities to improve patients’ lives. PK/PD modeling for drug pharmacokinetics and efficacy is routinely and successfully integrated […]

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IMIM (Fundació Institut Mar d’Investigacions Mèdiques)

Top: Juan Manuel Ramírez, Josep Saüch, Ferran Sanz, Miguel Angel Mayer, Angela Leis Machin, Lluis Domínguez.
Bottom: Francesco Ronzano, Alexia Giannoula, Judith Perez Granado, Laura I. Furlong, Janet Piñero, Emre Guney.

What is IMIM’s main focus? Our research group Integrative Biomedical Informatics, which belongs to IMIM (Institut Hospital del Mar d’Investigacions Mèdiques) and UPF (University of Pompeu Fabra) located in Barcelona, Spain, is focused on developing bioinformatic tools to gain insight from biomedical data for improving human health. We use  data mining and integration and natural […]

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ULIV (University of Liverpool)

Top: Chris Goldring, Lucia Livoti, Mark Pritchard, Giusy Russomanno, Rosalind Jenkins.
Bottom: Kevin Park, Carrie Duckworth, Ian Copple, Rowena Sison-Young, Colette Kelly

What is the University of Liverpool’s main focus? Here at the University of Liverpool we contribute to several aspects of TransQST including academic project management, wet laboratory experimentation in the areas of liver and gastrointestinal toxicity (GIT) and data interpretation associated with drug-induced liver injury (DILI). Our main scientific focus is to provide a better […]

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