Deliverables

Deliverable number Deliverable name Work package number Short Name of lead participant Dissemination level Delivery date
D4.1 Model selection process WP4 IMIM CO 28/02/2017
D3.1 Model compound and model selection process WP3 EMBL CO 31/03/2017
D1.1  Project Handbook WP1 SYNAPSE CO 30/04/2017
D2.1 Project communication plan and initial tool set  WP2 SYNAPSE CO 30/06/2017
D3.2 Data management platform requirements documentation WP3 EMBL CO 30/06/2017
D3.3 Data integration and curation plan WP3 EMBL CO 30/06/2017
D8.1 Gap analysis and GI experimental plan WP8 UM CO 30/06/2017
D2.2 Data and Knowledge management plan WP2 SYNAPSE CO 30/09/2017
D3.4 Model compound selection WP3 EMBL CO 30/09/2017
D4.2 Criteria for continuation or cessation of specific model development WP4 IMIM CO 30/09/2017
D1.2  Periodic report #1  WP1 ULIV CO 31/12/2017
D3.5 First release of the data management platform WP3 EMBL CO 31/12/2017
D4.3 Data models employed in downstream modelling methods  WP4 IMIM CO 31/12/2017
D6.1 Datasets for DIKI. WP6 EMBL CO 31/12/2017
D7.1 Report on modelling of potential anti-arrhythmogenic drugs on QTc prolongation and sudden cardiac death WP7 EMC CO 31/12/2017
D4.4 Biological pathways/modules relevant to build organ-specific dynamic models  WP4 IMIM CO 30/04/2018
D1.3  Periodic report #2  WP1 ULIV CO 31/12/2018
D1.4  Project assessment WP1 ULIV CO 31/12/2018
D4.5 First report on models developed on drug-organ toxicity events  WP4 IMIM CO 31/12/2018
D5.1 Report on QST model for DILI with WGCNA approach WP5 ULIV CO 31/12/2018
D5.2 Report on QST model for DILI with GSMN approach WP5 ULIV CO 31/12/2018
D7.2 Report on modelling of glucose lowering drugs on stroke, MI, cardiovascular comorbidity WP7 EMC CO 31/12/2018
D2.3 Interim Report on dissemination activities WP2 SYNAPSE CO 30/06/2019
D7.3 Report on multiscale models.  WP7 UOXF CO 30/06/2019
D1.5  Periodic report #3  WP1 ULIV CO 31/12/2019
D3.6 Second release of the data management platform WP3 EMBL CO 31/12/2019
D6.2 Renal PBPK models including renal injury biomarkers. WP6 SIMCYP CO 31/12/2019
D7.4 Report on the analysis of cardiotoxicity adverse outcomes pathways WP7 UOXF CO 31/12/2019
D7.5 Report on integration of PKPD modelling inpharmacoepidemiology WP7 EMC CO 31/12/2019
D8.2 PBPK-ADAM models expansion WP8 UM CO 31/12/2019
D8.3 Establishment of a characterised multi-cellular mouse/minipig/human organoid culture WP8 UM CO 31/12/2019
D6.3 Quantitative co-regulated gene networks WP6 UL CO 30/06/2020
D1.6  Periodic report #4  WP1 ULIV CO 31/12/2020
D3.7 Report on data integration and curation WP3 EMBL CO 31/12/2020
D4.6 Second report on models on drug-organ toxicity events  WP4 IMIM CO 31/12/2020
D8.4 Report on transcriptomic and functional data on dynamic intestinal toxicity  WP8 UM CO 31/12/2020
D3.8 Final release of the data management platform WP3 EMBL CO 30/06/2021
D3.9 Sustainability plan for models, data, and infrastructure WP3 EMBL CO 30/06/2021
D4.7 Workflows for the integration of modules and models for the description of drug-organ toxicity events WP4 IMIM CO 30/06/2021
D5.3 Report for mechanistic simulation WP5 ULIV CO 30/06/2021
D1.7  Periodic report #5  WP1 ULIV CO 31/12/2021
D2.4 Final Report on dissemination activities WP2 SYNAPSE CO 31/12/2021
D2.5 Report on regulatory interactions  WP2 SYNAPSE CO 31/12/2021
D2.6 Report on synergies with other initiatives  WP2 SYNAPSE CO 31/12/2021
D2.7 Final Data and Knowledge management plan WP2 SYNAPSE CO 31/12/2021
D4.8 Publication describing the entire modelling approach  WP4 IMIM CO 31/12/2021
D6.4 Translational QST models for DIKI.  WP6 IMIM CO 31/12/2021
D6.5 Novel assays for modelling QST.  WP6 UL CO 31/12/2021
D7.6 Model Development Report WP7 UL CO 31/12/2021
D7.7 Report on Translational Predictiveness WP7 UL CO 31/12/2021
D7.8 White paper on role of QST models in earlier recognition of potential adverse drug reactions WP7 EMC CO 31/12/2021
D7.9 Report on modelling of Snelder model in real life WP7 EMC CO 31/12/2021
D8.5 Report on multi-scale model for drug-induced and acute inflammation-mediated intestinal toxicity WP8 UM CO 31/12/2021