Fundació Institut Mar d’Investigacions Mèdiques (IMIM) participates in this project through the The Research Programme of Biomedical Informatics (GRIB) that is a joint research programme of the Hospital del Mar Medical Research Institute (IMIM) and the Pompeu Fabra University (UPF) located at the Barcelona Biomedical Research Park (PRBB).
GRIB carries out fundamental research and technological developments on the application of advanced information technologies and computational methods in the health and life sciences. GRIB brings together a multidisciplinary team of more than 60 scientists, as well as technical and management staff. It also has a wide experience in the development and application of computational methods in pharmaceutical R&D, as well as in collaborating with pharmaceutical companies in aspects such as knowledge management, bioinformatics and predictive modelling. GRIB has a long record of coordinating and participating in EU-funded projects and collaborations with pharmaceutical and biotechnological industry. It is the node for Biomedical Informatics of the Spanish Institute of Bioinformatics (INB) and participates also in the Bioinformatics Barcelona Association (BIB), which aims to promote training, research, and technology transfer in the field of Bioinformatics.
The GRIB is involved in the following projects related to TransQST:
EU-ToxRisk: An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century. Funded by the EU H2020 programme (2016-2021). iPiE: Intelligence-led Assessment of Pharmaceuticals in the Environment. Funded by the EU IMI programme(2015-2018). OpenPHACTS: An open, integrated and sustainable chemistry, biology and pharmacology knowledge resource for drug discovery. Funded by the EU IMI programme(2011-2016). eTOX: Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities. Funded by the EU IMI programme(2010-2016). Role in the project: Coordinator. EU-ADR: Early detection of adverse drug events by integrative mining of clinical records and biomedical knowledge. Funded by the EU FP7 programme (2008-2012).
Also developed the following tools:
eTOXlab: A modeling framework for the easy implementation, maintenance and publication as web services of in silico predictive models. DisGeNET: A knowledge platform on human diseases and their genes.