Translational Quantitative Systems Toxicology (TransQST) project outcomes have been included in a final booklet entitled “Advances in Quantitative Systems Toxicology – The premise of TransQST”. The booklet gathers all project results prior to January 2023 within a single document in an easy-to-read format and is available here.
Additionally, this page offers links to publicly accessible outcomes of TransQST. As many outcomes might only become accessible after the end of the project, this page focuses on providing query links to public resources, so that results always represent the current status, and continue to be up to date, even if the page is not maintained after the end of the funding period.
Models
Publicly available models either developed by the TransQST consortium or curated from the literature in the context of the project: TransQST Models.
Tools
Tools developed (or enhanced) and/or utilized by the TransQST consortium: TransQST Tools.
Data
Omics data
Gene expression data for liver, kidney, heart, and gastrointestinal tract that have been generated by, or curated within, the TransQST consortium are available via ArrayExpress: Gene expression data.
High-quality datasets with further curation and visualization are linked to the Expression Atlas Knowledge Base from the rightmost column (“Atlas”) in the query results above.
Proteomics data that have been generated by the TransQST consortium is available via PRIDE: Proteomics data.
Drug warning data
Data for withdrawn drugs or drugs with black box warnings that have been curated by the TransQST consortium is available via ChEMBL: Link.
Additional data
Additional data for liver, kidney, heart, and gastrointestinal tract that have been generated by, or curated within, the TransQST consortium includes histopathology, clinical chemistry, toxicokinetics, hemodynamic, and ion channel information. It is available via BioStudies: Link.
Publications
Scientific publications generated by the work of the TransQST consortium are available via ePMC, based on the query GRANT_ID:"116030" and related information: TransQST publications.